| プロフィール | |
|---|---|
| 専門分野 | 病理学、臨床病理学、免疫学、臨床免疫学、免疫遺伝学 |
| 学位 | 博士(医学) |
| 最終学歴 | 大東医学技術専門学校 臨床検査科, 放送大学 教養学部 |
| 着任年月日 | 2009-04-01 |
| 研究概要 | 1997年より、全身性自己免疫疾患であるSLE:全身性エリテマトーデスとRA：関節リウマチの発症メカニズムの解析と感受性遺伝子の同定をモデルマウスを用いておこなっている。
2003年より2004年まで、熊本大学 医学部 免疫学教室にてYaa遺伝子の遺伝子座と遺伝子の探索をおこなう。 2009年より、新規樹立した関節リウマチ自然発症モデルマウス（KO1）を用いたRA発症メカニズムの解析と治療実験をおこなっている。 2010年より、透明化した組織を用いて血管内からの特殊染色をおこなうための技術開発をおこなっている。また、1800年代の古い染色法の再現をおこなっている。 2016年より、新規樹立した疾患モデルマウスであるSLE発症B6.FcγRIIB-/-.YaaマウスおよびRA発症B6/129.FcγRIIB-/-マウスを用いて、単球とSLEおよびRAの病態との因果関係につい解析をおこなっている。 2023年より、色覚感受性が病理染色に与える影響について、研究をおこないはじめた。 |
| 教育概要 | 担当科目については、独自の資料集を作成している。疾患は臨床的な病態と病態の発症機序を検査データを交え教授している。また、医学総論、病理学、免疫学は科目間のつながりが強いため、知識を繋げる教育をおこなっている。 |
| 研究活動 | |
| 著書・論文 |
Yuya Hasunuma, Tomomi Shimizu, Mareki Ohtsuji, Yui Namikawa, Kentaro Ohnuma, Kaoru Yoshida, Yoshikazu Sawaguchi, Tomoaki Yonesaka, Yoshikazu Tokuoka, Yo Kodera. Latest Decade of Trends and Changes in the Pass Rate for the National Examination of Medical Technologist at the Department of Medical Technology, Toin University of Yokohama. Research bulletin, Toin University of Yokohama. 桐蔭横浜大学, 2022, 47, 85-92. doi::doi/10.50937/00000745
Yui Namikawa, Mareki Ohtsuji, Tomomi Shimizu. Health communication education required for Biomedical Laboratory Scientists pre-graduation. Research bulletin, Toin University of Yokohama. 桐蔭横浜大学, 2021, 45, 59-66. doi::doi/10.50937/00000519
Sachiko Hirose, Qingshun Lin, Mareki Ohtsuji , Hiroyuki Nishimura , J. Sjef Verbeek. 「Monocyte subsets involved in the development of systemic lupus erythematosus and rheumatoid arthritis」. International Immunology in press. 2019.
Qingshun Lin, Mareki Ohtsuji , Hirofumi Amano, Hiromichi Tsurui, Norihiro Tada, Ryota Sato, Hidehiro Fukuyama, Hiroyuki Nishimura, J. Sjef Verbeek, Sachiko Hirose. 「FcγRIIb on B cells and 1 myeloid cells modulates B cell activation and autoantibody」. The Journal of Immunology 2018 Dec 1.. 2018, 201(11):3199-3210..
Mareki Ohtsuji , Qingshun Lin, Hideki Okazaki , Kazuko Takahashi , Hirofumi Amano, Sachiko Hirose. “Anti-CD11b antibody treatment suppresses the osteoclast generation, inflammatory cell infiltration, and autoantibody production in arthritis-prone FcγRIIB-deficient mice”. Arthritis Research & Therapy 2018 Feb 8;20(1):25. doi: 10.1186/s13075-018-1523-1.. 2018, 201(11):3199-3210..
Mareki Ohtsuji , Qingshun Lin, Hideki Okazaki , Kazuko Takahashi , Hirofumi Amano, Sachiko Hirose. Anti-CD11b antibody treatment suppresses the osteoclast generation, inflammatory cell infiltration, and autoantibody production in arthritisprone FcγRIIB-deficient mice. Arthritis Research & Therapy. 2018, 20(1), 25.
Toshiaki Haga , Kenichi Mitsui, Junichi Toei, Mareki Ohtsuji , Yo Kodera, Kenichi Osada, Hiroyuki Nishimura. “Aberrant Light-Induced Depression Is Associated with Impaired Sensorimotor Gating in Mice”. World Journal of Neuroscience Vol.8 1-9, 2018, DOI: 10.4236/wjns.2018.81001. 2017.
Sachiko Hirose, Lin QINGSHUN, Mareki OHTSUJI , SJ Verbeek. “Role of inhibitory igg fc receptor iib on b cells and monocytes in yaa-related murine lupus”. Annals of the Rheumatic Diseases 76. 2017, 141.2-141.
ATIKEMU KELIMU, YUSUKE SUZUKI, MAREKI OTSUJI, SATOSHI HORIKOSHI, YASUHIKO TOMINO. “Influence of estrogen on the progression of kidney injury in murine IgA nephropathy”. Juntendo medical journal 63(3), 178-185, 2017. 2017.
Kodera Y , Ohtsuji M, Shirai T, Hirose S, Nishimura H. “enetic factors involved in the pathogenesis of systemic lupus erythematosus”. Autoimmune Dis Ther Approaches 2: 1-9. 2015.
Masaomi Obata, Mareki Ohtsuji, Yukiyasu Iida , Toshikazu Shirai , Sachiko Hirose , Hiroyuki Nishimura. “Genome-Wide Genetic Study in Autoimmune Disease-Prone Mice”. Methods in Molec. Biol.. 2014, pp.111-143.
Mareki Ohtsuji , Qingshun Lin , Keiko Nishikawa, Naomi Ohtsuji, Hideki Okazaki, Hiromichi Tsurui, Hirofumi Amano, Toshikazu Shirai , Sachiko Hirose. “IL-6 signal blockade ameliorates the enhanced osteoclastogenesis and”. Mod Rheumatol, 2014; Early Online: 1–8. 2014, ISSN 1439-7595 (print), 1439-7609 (online).
Masaomi Obata, Mareki Ohtsuji, Yukiyasu Iida, Toshikazu Shirai, Sachiko Hirose, Hiroyuki Nishimura. “Arthritis Reserch,Methods and Protocols”. Human press. 2014, 204.
Hideki Okazaki, Qingshun Lin, Keiko Nishikawa, Naomi Ohtsuji, Hiromichi Tsurui, Mareki Ohtsuji, Hirofumi Amano, Katsuko Sudo, Hiroyuki Nishimura, Toshikazu Shirai, Sachiko Hirose. “TNFα but not IL-17 is critical in the pathogenesis of rheumatoid arthritis spontaneously occurring in a unique FcγRIIB-deficient mouse model.”. Mod Rheumatol. in press. 2014.
Hideki Okazaki , Qingshun Lin , Keiko Nishikawa , Naomi Ohtsuji , Hiromichi Tsurui , Mareki Ohtsuji , Hirofumi Amano , Katsuko Sudo , Hiroyuki Nishimura , Toshikazu Shirai, Sachiko Hirose. “TNFα but not IL-17 is critical in the pathogenesis of rheumatoid arthritis spontaneously occurring in a unique FcγRIIB-deficient mouse model.”. Mod Rheumatol. 2014 Nov;24(6). 2014, pp.931-8..
Obata, M., Fujii, T. , Ohtsuji, M. , Kodera, Y. , Nishimura, H.. “Peripheral tolerance of antigen-specific Th cells induced with polyethylene glycol-conjugate of protein antigen.”. Open J. Immunol., 3. 2013, pp.62-70.
林青順, 西川桂子, 鶴井博理, 広瀬幸子, 大辻希樹, 西村裕之. 「自己免疫疾患におけるSLAMファミリー受容体の関与」. 臨床免疫. 2013, 60(3), 258-262頁.
大辻希樹、会田萌子. 「病理学における色素の役割と歴史」. 色材協会誌. 2013, 86(６)号, 212-216頁.
Obata M, Fujii T, Ohtsuji M , Kodera Y, Nishimura H. “Th cells induced with polyethylene glycol-conjugate of protein antigen”. Open J. Immunol., 3. 2013, pp.62-70.
Okazaki K, Suzuki Y, Ohtsuji M, Suzuki H, Kihara M, Kajiyama T, Hashimoto A, Nishimura H, Novak J, Brown R, Hall S, Izui S, Hirose S, and Tomino Y.. Development of a model of early-onset IgA nephropathy.. J Am Soc Nephrol .. 2012, 23(8), 1364-74. doi:DOI: 10.1681/ASN.2011121160
金子俊之, 天野浩文, 西川桂子, 河野晋也, 大辻希樹, 西村裕之, 廣瀬幸子, 高崎芳成. 「SLEとRAの疾患特異性を決定する遺伝要因の解析」. Japanese Journal of Clinical Immunology 35(4). 2012, 328頁.
Keiko Okazaki, Yusuke Suzuki , Mareki Otsuji , Hitoshi Suzuki, Masao Kihara , Tadahiro Kajiyama, Azusa Hashimoto, Hiroyuki Nishimura , Rhubell Brown , Stacy Hall , Jan Novak , Shozo Izui , Sachiko Hirose , Yasuhiko Tomino. “Development of a model of early-onset IgA nephropathy”. J Am Soc Nephrol. 2012 Aug;23(8). 2012, pp.1364-1374.
Kitabatake M, Toda T, Kuwahara K, Igarashi H, Ohtsuji M, Tsurui H, Hirose S, Sakaguchi N. “Transgenic Overexpression of G5PR That Is Normally Augmented in Centrocytes Impairs the Enrichment of High-Affinity Antigen-Specific B Cells, Increases Peritoneal B-1a Cells, and Induces Autoimmunity in Aged Female Mice”. J Immunol. 2012 Aug 1;189(3). 2012, pp.1193-1201.
Nobuaki SHIRAI, Mareki OHTSUJI, Keitaro HAGIWARA , Hiroki TOMISAWA, Naomi OHTSUJI, Sachiko HIROSE , Hiromi HAGIWARA. “Nephrotoxic effect of subchronic exposure to S-(1,2-dichlorovinyl)-L-cysteine in mice”. The Journal of Toxicological Science・37(5). 2012, pp.871-878.
Saito T, Musha Y , Miyakawa M , Itoh S, Ohtsuji M , Hanson MA, Takeda S. “Angiotensin II receptor antagonist reduces subsequent uterine arterial dysfunction in pregnant offspring of protein-restricted rat dams”. J Obstet Gynaecol Res. 2012 Mar;38(3). 2012, pp.483-489.
Shirai N, Ohtsuji M, Hagiwara K, Tomisawa H, Ohtsuji N, Hirose S, Hagiwara H.. Nephrotoxic effect of subchronic exposure to S-(1,2-dichlorovinyl)-L-cysteine in mice. . J Toxicol Sci .. 2012, 37(5), 871-8. doi:DOI: 10.2131/jts.37.871
Sato-Hayashizaki A, Ohtsuji M , Lin Q, Hou R , Ohtsuji N , Nishikawa K, Tsurui H , Ono M , Izui S , Shirai T , Takai T , Nishimura H , Hirose S. “Presumptive role of 129 strain-derived Sle16 locus in rheumatoid arthritis in a new mouse model with Fcγ receptor type IIb-deficient C57BL/6 genetic background”. Arthritis Rheum. 2011 Oct;63(10):. 2011, pp.2938-3930.
Fujii T, Hou R, Sato-Hayashizaki A, Obata M, Nishimura N, Ohtuji M, Ikeda K, Toei J, Mitsui K, Kodea Y, Shirai T, Hirose S, Nishimura H. “Susceptibility loci to for the defective foreign protein-induced tolerance in NZB mice: Implications of epistatic effects of Fcgr2b and Slam family genes”. Eur. J. Immunol. 2011. 2011, pp.2233-2240.
Musha Y, Itoh S, Miyakawa M, Ohtsuji M, Hanson MA, Kinoshita K, Takeda S. “Vascular, renal and placental effects on pregnant offspring of protein-restricted rat dams”. J Obstet Gynaecol Res. 2011 Apr;37(4). 2011, pp.343-351.
Fujii, T., Hou, R., Sato-Hayashizaki, A., Obata, M., Ohtsuji, M. , Ikeda, K., Mitsui, K., Kodera, Y. , Shirai, T., Hirose, S. , Nishimura H.. “Susceptibility loci for the defective foreign protein-induced tolerance in New Zealand Black mice: implication of epistatic effects of Fcgr2b and Slam family genes.”. Eur. J. Immunol., vol 41. 2011, vol 41, pp.2333-2340.
Obata, M., Fujiwara, R., Fujii, T., Kodera, Y. , Ohtsuji, M. , Hirose, S., Nishimura, H.. “Antigen-specific immune tolerance induced by protein antigens conjugated with polyethylene glycol.”. 桐蔭論叢 第22号. 2010, 第22号.
Masaomi OBATA, Ryu FUJIWARA, Takuma FUJII, Yo KODERA, Mareki OHTSUJI, Sachiko HIROSE and Hiroyuki NISHIMURA. "“Antigen-Apecific Immune Tolerance Induced by Protein Antigens Conjugated with Polyethlene Glycol” ". 桐蔭論叢 第22号. 2010, 第22号, pp.5-12.
Abe Y, Ohtsuji M, Ohtsuji N, Lin Q, Tsurui H, Nakae S, Shirai T, Sudo K, Hirose S.. Ankylosing enthesitis associated with up-regulated IFN-ganma and IL-17 production in (BXSB x NZB) F1 male mice: a new mouse model.. Mod Rheumatol .. 2009, 19(3), 316-22. doi:DOI: 10.1007/s10165-009-0166-0
Hou R, Ohtsuji M, Ohtsuji N, Zhang L, Adachi T, Hirose S, Tsubata T.. Centromeric interval of chromosome 4 derived from C57BL/6 mice accelerates type 1 diabetes in NOD.CD72 congenic mice.. Biochem Biophys Res Commun .. 2009, 380(1), 193-7. doi:10.1016/j.bbrc.2009.01.072.
Tsukamoto K, Ohtsuji M, Shiroiwa W, Lin Q, Nakamura K, Tsurui H, Jiang Y, Sudo K, Nishimura H, Shirai T, Hirose S.. Aberrant genetic control of invariant TCR-bearing NKT cell function in New Zealand mouse strains: possible involvement in SLE pathogenesis.. J Immunol .. 2008, 180(7), 4530-9. doi:10.4049/jimmunol.180.7.4530.
Nakamura K, Hirai H, Torashima T, Tsurui H, Xiu Y, Ohtsuji M, Lin Q, Tsukamoto K, Nishimura H, Ono M, Watanabe M, Hirose S.. CD3 and immunoglobulin G Fc receptor regulate cerebellar functions.. Mol Cell Biol .. 2007, 27(14), 5128-34. doi:10.1128/MCB.01072-06.
Shiroiwa W, Tsukamoto K, Ohtsuji M, Lin Q, Ida A, Kodera S, Ohtsuji N, Nakamura K, Tsurui H, Kinoshita K, Nishimura H, Shirai T, Hirose S.. IL-4R alpha polymorphism in regulation of IL-4 synthesis by T cells: implication in susceptibility to a subset of murine lupus. Int. Immunol.. Int Immunol .. 2007, 19(2), 175-83. doi:10.1093/intimm/dxl134.
Nakamura K, Koyama Y, Takahashi K, Tsurui H, Xiu Y, Ohtsuji M, Lin Q, Sugawara Y, Sawabe K, Ohashi A, Ohnuma T, Arai H, Nishimura H, Hasegawa H, Hirose S.. Requirement of Tryptophan Hydroxylase During Development for Maturation of Sensorimotor Gating. . J Mol Biol .. 2006, 363(2), 345-54. doi:DOI: 10.1016/j.jmb.2006.08.051
Lin Q, Xiu Y, Jiang Y, Tsurui H, Nakamura K, Kodera S, Ohtsuji M, Ohtsuji N, Shiroiwa W, Tsukamoto K, Amano H, Amano E, Kinoshita K, Sudo K, Nishimura H, Izui S, Shirai T, Hirose S.. Genetic dissection of the effects of stimulatory and inhibitory IgG Fc receptors on murine lupus.. J Immunol .. 2006, 177(3), 1646. doi:DOI: 10.4049/jimmunol.177.3.1646
Nakamura K, Sugawara Y, Sawabe K, Ohashi A, Tsurui H, Xiu Y, Ohtsuji M, Lin Q, Nishimura H, Hasegawa H, Hirose S.. Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels. . J. Neurosci. 2006, 26(2), 530-4. doi:DOI: 10.1523/JNEUROSCI.1835-05.2006
Fujii H, Gabrielson E, Takagaki T, Ohtsuji M, Ohtsuji N, Hino O. Frequent down-regulation of HIVEP2 in human breast cancer. . Breast Cancer Res Treat .. 2005, 91(2), 103-12. doi:DOI: 10.1007/s10549-004-5779-6
Wen X, Zhang D, Kikuchi Y, Jiang Y, Nakamura K, Xiu Y, Tsurui H, Takahashi K, Abe M, Ohtsuji M, Nishimura H, Takatsu K, Shirai T, Hirose S.. Transgene-hyper-expression of IL-5 inhibits autoimmune disease but increases the risk of B-cell chronic lymphocytic leukemia in a model of murine lupus. . 2004, 34(10), 2740-9. doi:DOI: 10.1002/eji.200425267
Li N, Nakamura K, Jiang Y, Tsurui H, Matsuoka S, Abe M, Ohtsuji M, Nishimura H, Kato K, Kawai T, Atsumi T, Koike T, Shirai T, Ueno H, Hirose S.. Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus.. Hum. Mol. Genet.. 2004, 13(2), 171-9. doi:DOI: 10.1093/hmg/ddh020
Matsuoka S, Tsurui H, Abe M, Terashima K, Nakamura K, Hamano Y, Ohtsuji M, Honma N, Serizawa I, Ishii Y, Takiguchi M, Hirose S, Shirai T.. A monoclonal antibody to the alpha2 domain of murine major histocompatibility complex class I that specifically kills activated lymphocytes and blocks liver damage in the concanavalin A hepatitis model.. J. Exp. Med. 2003, 198(3), 497-503.. doi:DOI: 10.1084/jem.20021301
Nakamura K, Xiu Y, Ohtsuji M, Sugita G, Abe M, Ohtsuji N, Hamano Y, Jiang Y, Takahashi N, Shirai T, Nishimura H, Hirose S.. Genetic dissection of anxiety in autoimmune disease.. Hum Mol Genet.. 2003, 12(10), 1097-86. doi:10.1093/hmg/ddg128.
Miura-Shimura Y, Nakamura K, Ohtsuji M, Tomita H, Jiang Y, Abe M, Zhang D, Hamano Y, Tsuda H, Hashimoto H, Nishimura H, Taki S, Shirai T, Hirose S.. C1q regulatory region polymorphism down-regulating murine C1q protein levels with linkage to lupus nephritis.. J. Immunol.. 2002, 169(3), 1334-9. doi:DOI: 10.4049/jimmunol.169.3.1334
Fujii H, Matsumoto T, Yoshida M, Furugen Y, Takagaki T, Iwabuchi K, Nakata Y, Takagi Y, Moriya T, Ohtsuji N, Ohtsuji M, Hirose S, Shirai T.. Genetics of synchronous uterine and ovarian endometrioid carcinoma: combined analyses of loss of heterozygosity, PTEN mutation, and microsatellite instability.. Hum Pathol .. 2002, 33(4), 421-8. doi:10.1053/hupa.2002.124118.
Jiang Y, Hirose S, Abe M, Sanokawa-Akakura R, Ohtsuji M, Mi X, Li N, Xiu Y, Zhang D, Shirai J, Hamano Y, Fujii H, Shirai T.. Polymorphisms in IgG Fc receptor IIB regulatory regions associated with autoimmune susceptibility. . Immunogenetics. 2000, 51(6), 429-35.. doi:10.1007/s002510050641.
Jiang Y, Ohtsuji M, Abe M, Li N, Xiu Y, Wen S, Shirai T, Hirose S.. Polymorphism and chromosomal mapping of the mouse gene for B-cell activating factor belonging to the tumor necrosis factor family (Baff) and association with the autoimmune phenotype. . Immunogenetics. 2001, 53(9), 810-813. doi:10.1007/s00251-001-0396-6.
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| 研究発表等 |
大辻希樹. "教育講演 １世紀にわたり変わらぬ HE 染色の魅力". 第73回日本医学検査学会. 金沢, 2024.
Sachiko HIROSE, Qingshun LIN,Kazuko Takahashi, Mareki Ohtsuji, Hiroyuki NISHIMURA, J.Sjef.VERBEEK. "Novel pathway of autoreactive B cell activation by Inhibitory IgG Fc receptor IIb-deficient monocytes". ISBME2017. 桐蔭横浜大学, 2023.
Kazuko Takahashi, Mareki Ohtsuji, Kenichi Mitsui, Yo Kodera, Sachiko Hirose , Sjef J.Verbeek and Hiroyuki Nishimura. "Roles of inhibitory Fc receptor FcgRIIB on the peripheral B cell tolerance". ISBME2022. 桐蔭横浜大学, 2022.
Junichi Toei, Toshiaki Haga, Noriko Iida, Tomoo Ueno, Mareki Ohtsuji, Yo Kodera , Kenichi Mitsui and Hiroyuki Nishimura. "Rodent Behavior Analysis Instruments for Behavioral Neuroscience". ISBME2022. 桐蔭横浜大学, 2022.
Junichi Toei, Toshiaki Haga, Noriko Iida, Tomoo Ueno, Mareki Ohtsuji, Yo Kodera , Kenichi Mitsui and Hiroyuki Nishimura. "Mouse Activity Monitoring System for Behavioral Neuroscience". ISBME2021. 桐蔭横浜大学, 2021.
Kazuko Takahashi, Mareki Ohtsuji, Kenichi Mitsui, Yo Kodera, Sachiko Hirose , Sjef J.Verbeek and Hiroyuki Nishimura. "Roles of inhibitory Fc receptor FcgRIIB on the peripheral B cell tolerance". ISBME2021. 桐蔭横浜大学, 2021.
Noriko Iida, Toshiaki Haga, Junichi Toei, Kenichi Mitsui, Mareki Ohtsuji, Yo Kodera, Kazuko Takahashi and Hiroyuki Nishimura. "Disrupted Circadian Rhythm in Mouse Model of Major Depressive Disorder ". ISBME2021. 桐蔭横浜大学, 2021.
Junichi Toei, Toshiaki Haga, Noriko Iida, Tomoo Ueno, Mareki Ohtsuji, Yo Kodera, Kenichi Mitsui and Hiroyuki Nishimura. "Mouse Activity Monitoring System for Behavioral Neuroscience". ISBME2021. 2021.
Kazuko Takahashi, Mareki Ohtsuji, Qingshun Lin, J. Sjef Verbeek, Hiroyuki Nishimura and Sachiko Hirose. "Combined Effect of FcgRIIB Deficiency and SLAM129 on the Spontaneous Development of Murine Rheumatoid Arthritis-like Disease". ISBME2020. 桐蔭横浜大学, 2020.
Noriko Iida, Toshiaki Haga, Junichi Toei, Kenichi Mitsui, Mareki Ohtsuji, Yo Kodera Kazuko Takahashi and Hiroyuki Nishimura. "Circadian Phase-Shifting in Mouse Model of Major Depressive Disorder". ISBME2020. 桐蔭横浜大学, 2020.
Junichi Toei, Toshiaki Haga, Noriko Iida, Tomoo Ueno, Mareki Ohtsuji, Yo Kodera and Hiroyuki Nishimura. "Mouse Activity Monitoring System for Behavioral Neuroscience". ISBME2020. 桐蔭横浜大学, 2020.
佐藤悠衣, 西ノ村瑠南, 齊藤明日香, 遠藤百恵, 平石胡桃, 田中萌, 田口紗希, 大辻希樹. "単球の活性化と自己免疫疾患発症の関連性". 第69回日本医学検査学会. 仙台, 2020.
西ノ村瑠南, 佐藤悠衣, 岩田智久, 田口紗希, 門倉香織, 杉﨑由季, 杉山真由佳, 大辻希樹. "好中球機能異常とSLE発症メカニズムの関係". 第69回日本医学検査学会. 仙台, 2020.
Mareki Ohtsuji , Qingshun Lin, Hidehiro Fukuyama , Hirofumi Amano , Hiroyuki Nishimura , J. Sjef Verbeek, Sachiko Hirose. "「 Contribution of monocyte subsets in autoimmune diseases.」". The 48th Annual Meeting of Japanese Society for Immunology , Hamamatsu, Japan. Hamamatsu, Japan, 2019.
Noriko Iida, Toshiaki Haga, Junichi Toei, Kenichi Mitsui, Mareki Ohtsuji, Yo Kodera Kazuko Takahashi and Hiroyuki Nishimura. "Aberrant Light-Induced Depression Is Associated with Impaired Sensorimotor Gating in Mice". ISBME2019. 2019.
Junichi Toei, Toshiaki Haga, Noriko Iida, Tomoo Ueno, Mareki Ohtsuji, Yo Kodera and Hiroyuki Nishimura. "Mouse Activity Monitoring System for Neurogenetic Research". ISBME2019. 桐蔭横浜大学, 2019.
Kazuko Takahashi , Mareki Ohtsuji , Qingshun Lin, Hideki Okazaki , Hirofumi Amano , Hideo Yagita , Hiroyuki Nishimura , Sachiko Hirose. "「Anti-CD11b antibody treatment suppresses the disease conditions in rheumatoid arthritis (RA)-prone, FcγRIIB-deficient mice」". IMMUNOLOGY 2019 , SAN DIEGO CONBENTION CENTER. SAN DIEGO CONBENTION CENTER, 2019.
OHTSUJI Mareki , AMANO Hirofumi , OKAZAKI Hieki , NISHIMURA Hiroyuki , HIROSE Sachiko. "「Anti-CD11b antibody treatment suppresses the osteoclast generation, inflammatory cell infiltration, and autoantibody production in arthritis-prone FcγRIIB-deficient mice.」". The 63st Annual General Assembly and Scientific Meeting of the Japan College Rheumatology , Kyoto,Japan. Kyoto,Japan, 2019.
Hiroyuki Nishimura, Masaomi Obata, Mareki Ohtsuji, Yo Kodera, Toshiyuki Takai, Katsuko Sudo, J.Sjef Verbeek, Sachiko Hirose. "「Epistatic interaction between fcgr2b and Slam family genes in susceptibility to defective foreign protein-induced tolerance」". The 47th Annual Meeting of Japanese Society for Immunology. 2018.
Mareki Ohtsuji, Qingshun Lin, Hirofumi Amano, Hideo Yagita , Kazuko Takahashi, Hideki Okazaki, Hiroyuki Nishimura, Hirose Sachiko. "「Treatment with anti-CD11b antibody ameliorates arthritis in novel arthritis-prone mouse model」". The 47th Annual Meeting of Japanese Society for Immunology Fukuoka, Japan（2018年12月10～12日）. Fukuoka, Japan, 2018.
Miho Takahashi, Junichi Toei, Toshiaki Haga, Kazuko Takahashi, Mareki Ohtsuji ,Tomoo Ueno, Yo Kodera, Kenichi Osada and Hiroyuki Nishimura. "Aberrant Light-Induced Depression is Associated with Impaired Sensorimotor Gating in Mice". ISBME2018. 桐蔭横浜大学, 2018.
Sachiko HIROSE, Mareki OHTSUJI, Qingshun LIN,Kazuko TAKAHASHI, Hiroyuki NISHIMURA, J.Sjef.VERBEEK. "Ameriolation of rheumatoid arthritis-like disease by treatment with anti-CD11b antibody in arthritis-prone FcRIIB-deficient mice". ISBME2018. 桐蔭横浜大学, 2018.
菱沼 春華, 平石 胡桃, 遠藤 百恵, 久保田 千晴, 齊藤 明日香, 石井 大和, 櫻井 百花, 山田 理雄, 大辻 希樹. "「抗CD11b抗体投与によるKO1マウスに自然発症する関節炎の抑制効果」". 第13回日本臨床検査学教育学会学術大会 札幌（2018年8月17～20日）. 札幌, 2018.
久保田 千晴, 平石 胡桃, 齊藤 明日香, 菱沼 春華, 遠藤 百恵, 石井 大和, 櫻井 百花, 山田 理雄, 大辻 希樹. "「関節リウマチに対する新規抗体治療法の検討」". 第13回日本臨床検査学教育学会学術大会 札幌（2018年8月17～20日）. 札幌, 2018.
遠藤 百恵, 岩田 智久, 加藤 紗希, 門倉 香織, 田中 萌, 杉埼 由季, 杉山 真由佳, 大辻 希樹. "「G-CSF遺伝子多型が好中球機能に及ぼす影響」". 第13回日本臨床検査学教育学会学術大会 札幌（2018年8月17～20日）. 札幌コンベンションセンター（北海道札幌市）, 2018.
齊藤 明日香, 平石 胡桃, 遠藤 百恵, 久保田 千晴, 菱沼 春華, 渡辺 祥子, 大辻 希樹. "「抗CD11b抗体投与によるFcgRIIB欠損マウスに自然発症する関節炎の抑制効果」". 第67回 日本医学検査学会（2018年5月12 〜13日）. 2018.
OHTSUJI Mareki, LIN Qingshun, AMANO Hirofumi, OKAZAKI Hieki , NISHIMURA Hiroyuki, HIROSE Sachiko. "「Anti-cd11b antibody treatment prevents rheumatoid arthritis (RA) like disease in a novel RA-prone FcgRIIB -deficient mouse model.」". 第62回 日本リウマチ学会総会・学術集会（2018/4/26 〜28）. 2018.
Mareki Ohtsuji, Qingshun Lin, Hirofumi Amano , Hideo Yagita , Kazuko Takahashi , Hideki Okazaki , Hiroyuki Nishimura , Hirose Sachiko. "“Inhibitory effect of the blocking of monocyte recruitment from the blood on spontaneously occurring”". The 46th Annual Meeting of The Japanese Society for Immunology Sendai International Center（2017年12月12日～14日）. Sendai International Center, 2017.
Hiroyuki Nishimura , Masaomi Obata, Mareki Ohtsuji , Yo Kodera , Toshiyuki Takai, Katsuko Sudo, Sachiko Hirose. "“Epistatic interaction between fcgr2b and Slam family genes in susceptibility to defective foreign proteininduced”". The 46th Annual Meeting of The Japanese Society for Immunology Sendai International Center（2017年12月12日～14日）. Sendai International Center, 2017.
Sachiko Hirose, Qingshun Lin, Mareki Ohtsuji, Hirofumi Amano, Hidehiro Fukuyama, Hiroyuki Nishimura, Sjef Verbeek. "“Independent effect of inhibitory IgG Fc receptor IIB on B cells and monocytes on Yaa-induced murine”". The 46th Annual Meeting of The Japanese Society for Immunology Sendai International Center（2017年12月12日～14日）. Sendai International Center, 2017.
S. Hirose, L. Qingshun, M. Ohtsuji, H. Nishimura , H. Amano, S. J. Verbeek. "“ROLE OF INHIBITORY IGG FC RECEPTOR IIB ON B CELLS AND MONOCYTES IN YAA-RELATED MURINE”". EULAR 2017(欧州リウマチ学会議 ) Madrid(Reino de España)（2017年6月14日～17日）. Madrid, 2017.
大辻 希樹, 林 青順, 天野 浩文, 岡崎 英規, 西村 裕之, 広瀬 幸子. "「抗CD11b投与によるFcgRⅡB欠損マウスに自然発症する関節炎の抑制効果」". 第61回 日本リウマチ学会総会・学術集会 福岡国際会議場. 福岡国際会議場, 2017.
広瀬 幸子, 林 青順, 大辻 希樹 , 天野 浩文 , 西村 裕之. "「ループス腎炎の発症におけるIgG Fc receptor ⅡB欠損の役割に関する細胞レベルでの解析」". 第61回 日本リウマチ学会総会・学術集会 福岡国際会議場. 福岡国際会議場, 2017.
OHTSUJI Mareki,LIN Qingshun,OKAZAKI Hideki,IKEDA Shuri,SASAKI Hinako,AMANO Hirofumi,YAGITA Hideo,NISHIMURA Hiroyuki,HIROSE Sachiko. "Blocking of CD11b+ cell-migration ameliorates rheumatoid arthritis-like disease spontaneously occurring in a unique FcgRIIB-deficient mouse model". 日本免疫学会 沖縄. 2016.
OHTSUJI Mareki, LIN Qingshun, OKAZAKI Hideki, IKEDA Shuri, Hinako, AMANO Hirofumi, YAGITA Hideo, NISHIMURA Hiroyuki, HIROSE Sachiko. "Blocking of CD11b+ cell-migration ameliorates rheumatoid arthritis-like disease spontaneously occurring in a unique FcgRIIB-deficient mouse model". 日本免疫学会. 沖縄, 2016.
LIN Qingshun , TSURUI Hiromichi , AMANO Hirohumi, NISHIKAWA Keiko, OHTSUJI Mareki , NISHIMURA Hiroyuki , J.Sjef.Verbeek , HIROSE Sachiko. "“Inhibitory IgG Fc receptor IIB on B cells and monocytes independenly controls Yaa-induced murine lupus”". 日本免疫学会 沖縄（2016年12月5日～7日）. 沖縄, 2016.
NISHIMURA Hiroyuki, FUJII Takuma , OBATA Masaomi, OHTSUJI Mareki , KODERA Yo , TAKAI Toshiyuki , SUDO Katsuko , HIROSE Sachiko. "“Epistatic interaciton between fcgr2b and Slam family genes in susceptibility to defective foreign proteininduced tolerance”". 日本免疫学会 沖縄（2016年12月5日～7日）. 沖縄コンベンションセンター, 2016.
Lin Qingshun , Tsurui Hiromichi , Keiko Nishikawa, Amano Hirofumi, Ohtsuji Mareki, Nishimura Hiroyuki , Shirai Toshikazu , J.Sjef.Verbeek , Hirose Sachiko. "“Cell Type-specific role of inhibitory IgG Fc receptor ⅡB in Yaa-induced murine lupus”". The 44th Annual Meeting of japanese Society for Immunology Sapporo Conbebtion Center. Sapporo Conbebtion Center, 2015.
Keiko Nishikawa , Lin Qingshun , Tsurui Hiromichi , Amano Hirofumi, Okazaki Hideki , Ohtsuji Mareki, Shirai Toshikazu , Hirose Sachiko , Nishimura Hiroyuki. "“Role of inhibitory FcγRⅡb and autoimmune-prone SLAM haplotype in autoimmune disease”". The 44th Annual Meeting of japanese Society for Immunology Sapporo Conbebtion Center. Sapporo Conbebtion Center, 2015.
Hirono Fusako, Obata Masaomi , Kodera Yo, Ohtsuji Mareki, Shirai Toshikazu, Hirose Sachiko, Nishimura Hiroyuki. "“Genetic control of the abnomal activation and sequestrarion of splenic CD4+ Tcells in autoimmune diseaseprone (NZB x NZW)F1 hybrid mice”". The 44th Annual Meeting of japanese Society for Immunology Sapporo Conbebtion Center. 2015.
林青順 , 西川桂子, 大辻希樹, 天野浩文 , 西村裕之 , 白井俊一 , 広瀬幸子. "「細胞特異的FcγRⅡB発現欠損マウスの樹立によるYaa誘導ループス腎炎発症機序の解明」". 第59回 日本リウマチ学会・総会名古屋国際会議場. 名古屋国際会議場, 2015.
Fusako Hirono, Mareki Ohtsuji, Hiroyuki Nishimura and Sachiko Hirose. "A Mouse Model of Rheumatoid Arthritis : IL-6 Receptor–Specific Monoclonal Antibody Blocked Arthritis". ISBME2015. 桐蔭横浜大学, 2015.
大辻 希樹 , 林 青順 , 西川 桂子 , 岡崎 英規 , 天野 浩文 , 西村 裕之 , 西本 憲弘, 白井 俊一, 広瀬 幸子. "“Preventive and therapeutic effects of anti-IL-6 receptor antibody on spontaneously occurring rheumatoid arthritis in an FcRIIB-deficient mouse model ”". 第59回 日本リウマチ学会・総会名古屋国際会議場. 名古屋国際会議場, 2015.
Hirosa Fusako, Obata Masaomi , Kodera Yo , Ohtsuji Mareki , Shirai Toshikazu, Hirose Sachiko , Nishimura Hiroyuki. "“Gene expression profile in spleen cells of (NZB x NZW)F1 mice with overt SLE activity”". 第43回日本免疫学会総会・学術集会 京都. 京都, 2014.
Qingshun Lin , Turui Hirimichi , Nishikawa Keiko , Amano Hirofumi , Ohtsuji Mareki , Nishimura Hiroyuki, Shirai Toshikazu , Verbeek.J.Sjef , Hirose Sachiko. "“B cell specific FcγRIIb deficiency is enough for autoantibody production, but not for the progression of Yaa-related severe lupus nephritis”". 第43回日本免疫学会総会・学術集会 京都. 京都, 2014.
Mareki Ohtsuji , Hideki Okazaki , Qingshun Lin , Keiko Nishikawa , Hiroyuki Nishimura , Hirofumi Amano , Norihiro Nishimoto , Toshikazu Shirai , Sachiko Hirose. "“TNFα and IL-6 but not IL-17 are critical in the pathogenesis of rheumatoid arthritis spontaneously occurring in a unique FcRIIB-deficient mouse model.”". 第43回日本免疫学会総会・学術集会 京都. 京都, 2014.
HIRONO Fusako, OBATA Masaomi, KODERA Yo, OHTSUJI Mareki, SHIRAI Toshikazu, HIROSE Sachiko, NISHIMURA Hiroyuki. "Gene Expression Profile in Spleen Cells of Autoimmune-prone (NZB x NZW)F1 Mice". ISBME2014. 桐蔭横浜大学, 2014.
Qingshun Lin, Keiko Nishikawa, Mareki Ohtsuji, Hiroyuki Nishimura, Hirofumi Amano, Sachiko Hirose. "“B cell specific deficiency of FcγRIIB is required for autoantibody production,but not enough for early onset lupus nephritis in B6.Yaa mice”". 第58回日本リウマチ学会総会・学術集会（東京）. 東京, 2014.
Mareki Ohtsuji, Qingshun Lin, Keiko Nishikawa, Hideki Okazaki, Hiroyuki Nishimura, Norihiro Nishimoto, Sachiko Hirose. "“IL-6 signal blockade ameliorates spontaneously occurring rheumatoid arthritis in an FcγRIIB-deficient mouse model through loss of RANKL/OPG balance”". 第58回日本リウマチ学会総会・学術集会（東京）. 東京, 2014.
Masaomi Obata, Mareki Ohtsuji , Toshikazu Shirai, Sachiko Hirose, Hiroyuki Nishimura. "“Peripheral tolerance of antigen-specific Th cell induced with polyethylene glycol-conjugate of protein antigen.”". 第42回日本免疫学会学術集会. 2013.
OBATA Masaomi, OHTSUJI Mareki, HIRAI Toshikazu, HIROSE Sachiko, NISHIMURA Hiroyuki. "“Peripheral tolerance of antigen-specific Th cells induced with polyethylene glycol-conjugate of protein antigen.”". 第42回 日本免疫学会総会・学術集会記録（幕張）. 幕張, 2013.
LIN Qingshun, NISHIKAWA Keiko, TSURUI Hiromichi, OKAZAKI Hideki, OHTSUJI Mareki, NISHIMURA Hiroyuki, AMANO Hirofumi, SHIRAI Toshikazu, HIROSE Sachiko. "“B cell specific deficiency of FcgRIIB results in high levels of autoantibodies without severe lupus nephritis in C57BL/6.Yaa mice.”". 第42回 日本免疫学会総会・学術集会記録（幕張）. 幕張, 2013.
OKAZAKI Hideki, LIN Qingshun, NISHIKAWA Keiko, TSURUI Hiromichi, OHTSUJI Mareki, NISHIMURA Hiroyuki, SHIRAI Toshikazu, HIROSE Sachiko. "“Blockade of TNFa, but not IL-17, ameliorates spontaneously occurring autoimmune arthritis in FcgRIIB-deficient mice.”". 第42回 日本免疫学会総会・学術集会記録（幕張）. 幕張メッセ 国際会議場(千葉県千葉市）, 2013.
Masaomi Obata, Mareki Ohtsuji, Toshikazu Shirai, Sachiko Hirose and Hiroyuki Nishimura. "Peripheral tolerance of antigen-specific Th cells induced with polyethylene glycol-conjugate of protein antigen". ISBME2013. 桐蔭横浜大学, 2013.
Obata, M, Fujii, T , Ohtsuji, M , Kodera, Y, Nishimura, H. "“Peripheral tolerance of antigen-specific Th cell induced with polyethylene glycol-conjugate of protein antigen.”". 8th TOIN International Symposium on Biomedical Engineering. 2013.
Toshiyuki Kaneko, Hirofumi Amano, Mareki Ohtsuji, Keiko Nishikawa, Shinya Kawano, Naomi Ohtsuji, Qingshun Lin, Toshikazu Shirai, Yoshinori Takasaki, Sachiko Hirose. "“A novel locus of B6 mice on chromosome 12 plays a role in common process shared by SLE, RA, and Sj_gren syndrome.”". The 5th East Asian Group of Rheumatology（ソウル・韓国）. ソウル・韓国, 2013.
OBATA Masaomi, OHTSUJI Mareki, SHIRAI Toshikazu, HIROSE Sachiko, NISHIMURA Hiroyuki. "“Mechanism of Th cell tolerance induced with tolerogenic polyethylene glycol(PEG)-conjugate of protein antigen”". 第41回 日本免疫学会総会・学術集会（神戸）. 神戸, 2012.
LIN Qingshun, TSURUI Hiromichi, NISHIKAWA Keiko, OKAZAKI Hideki, OHTSUJI Mareki, NISHIMURA Hiroyuki, ONO Masao, SHIRAI Toshikazu, HIROSE Sachiko. "“The role of SAP-signal in SLE”". 第41回 日本免疫学会総会・学術集会（神戸）. 神戸, 2012.
KITABATAKE Masahiro, TODA Teppei, KUWAHARA Kazuhiro, IGARASHI Hideya, OHTSUJI Mareki, HIROSE Sachiko, SAKAGUCHI Nobuo. "“Servival of antigen-derived germinal center B-cell is controlled by centrocyte-associated expression of apoptosis-regulator G5PR.”". 第41回 日本免疫学会総会・学術集会（神戸）. 神戸, 2012.
KANEKO Toshiyuki, AMANO Hirofumi, OHTSUJI Mareki, NISHIKAWA Keiko, KAWANO Shinya, OHTSUJI Naomi, TAKASAKI Yoshinar, Lin Qingshun, OKAZAKI Hideki, HIROSE Sachiko. "“A novel locus of B6 mice on chromosome 12 plays a role in common process shared by SLE, RA, and Sjögren syndrome.”". 第41回 日本免疫学会総会・学術集会（神戸）. 神戸, 2012.
"「からだを守る免疫の不思議な世界」". 桐蔭横浜大学 ジュニア公開講座. 桐蔭横浜大学, 2012.
Obata, M, Kodera, Y , Ohtsuji, M, Shirai, T, Hirose, S , Nishimura, H. "“Mechanism of Th-cell tolerance induced with the tolerogenic protein antigen conjugated with polyethylene glycol.”". 7th TOIN International Symposium on Biomedical Engineering. 2012.
Masaomi Obata, Takuma Fujii,Kenichi Mitsui, Yo Kodera1, Mareki Ootuji , Toshikazu Shirai ,Sachiko Hirose and Hiroyuki Nishimura1. "Mechanism of Th-cell tolerance induced with the tolerogenic protein antigen conjugated with polyethylene glycol". ISBME2012. 桐蔭横浜大学, 2012.
広瀬幸子, 佐藤 綾, 林 青順, 天野浩文, 大辻希樹, 西村裕之. "「篤な関節リウマチを自然発症するFcγレセプターIIB欠損マウスの樹立」". 56回日本リウマチ学会総会・学術集会・国際リウマチシンポジウムプログラム・抄録集（東京）. 東京, 2012.
"「からだを守る免疫の不思議な世界」". 桐蔭横浜大学 ジュニア公開講座. 桐蔭横浜大学, 2011.
藤原 龍, 尾畑賢臣, 藤井琢磨, 大辻希樹, 小寺 洋, 広瀬幸子, 西村裕之. "「ポリエチレングリコール修飾抗原により誘導されるTh細胞免疫寛容の機序」". 第40回日本免疫学会学術集会・学術集会（千葉幕張）. 千葉幕張, 2011.
林 青順, 大辻希樹, 佐藤 綾, 大辻奈穂美, 西川桂子, 鶴井博理, 須藤カツ子, 西村裕之, 小野栄夫, 白井俊一, 広瀬幸子. "「SLEにおけるSLAMシグナルの役割」". 第40回日本免疫学会学術集会・学術集会（千葉幕張）. 千葉幕張, 2011.
佐藤 綾, 大辻希樹, 林 青順, 大辻奈穂美, 西川桂子, 鶴井博理, 小野栄夫, 白井俊一, 高井俊行, 西村裕之, 広瀬幸子. "「関節リウマチ発症に与えるSle16領域の影響」". 第40回日本免疫学会学術集会・学術集会（千葉幕張）. 千葉幕張, 2011.
Hiroki IKEDA, Mareki OHTSUJI, Masaomi OBATA, Yo KODERA, Hiroyuki NISHIMURA. "“Interleukin 21 Chemically Conjugated with Polyethylene Glycol: Potential Application in Ttumor Immunotherapy”". 6th TOIN International Symposium on Biomedical Engineering 2011, Toin University of Yokohama. Toin University of Yokohama, 2011.
安藤誠一郎, 天野浩文, 天野恵理, 箕輪健太郎, 渡邉崇, 仲野総一郎, 森本真司, 戸叶嘉明, 林青順, 侯蓉, 大辻希樹, 広瀬幸子, 高崎芳成. "「FTY720治療後のBXSBマウス腎炎における腎臓局所サイトカイン・ケモカイン発現の変化」". 第55回日本リウマチ学会総会学術集会（神戸）. 神戸, 2011.
白井信明 , 大辻希樹, 富澤宏樹, 萩原啓実. "「マウスにおけるトリクロロエチレン代謝産物DCVCの腎毒性」". 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会 神戸ポートアイランド. 神戸ポートアイランド, 2010.
"「からだを守る免疫の不思議な世界」". 桐蔭横浜大学 ジュニア公開講座. 桐蔭横浜大学, 2010.
Masaomi OBATA, Ryu FUJIWARA, Takuma FUJII, Yo KODERA, Mareki OHTSUJI, Sachiko HIROSE, Hiroyuki NISHIMURA. "“Genetic Studies on Immune Tolerance”". TOIN International Symposium on Biomedical Engineering 2010, Toin University of Yokohama. Toin University of Yokohama, 2010.
Kanami FUKUNAGA, Yukari AIZAWA, Yukiho OGAWA, Azusa MORINAGA, Mareki OHTSUJI, Toshikazu SHIRAI, Yo KODERA, Sachiko HIROSE, Hiroyuki NISHIMURA. "“Role of autoimmunity in the development of ankylosing enthesitis in (BXSB x NZB)F1 male mice”". TOIN International Symposium on Biomedical Engineering 2010, Toin University of Yokohama. Toin University of Yokohama, 2010.
Ryu FUJIWARA, Ken FUKUMORI, Masaomi OBATA, Takuma FUJII, Mareki OHTSUJI, Yo KODERA, Sachiko HIROSE, Hiroyuki NISHIMURA. "“Differential responses of ovalbumin-specific Th cells towards chemically-modified immunogenic and tolerogenic ovalbumins”". TOIN International Symposium on Biomedical Engineering 2010, Toin University of Yokohama. 2010.
Yukari AIZAWA, Kanami FUKUNAGA, Mareki OHTSUJI, Toshikazu SHIRAI, Yo KODERA, Sachiko HIROSE, Hiroyuki NOSHIMURA. "“The role of SAP (SLAM-associated protein) gene in the pathogenesis of Systemic Lupus Erythematosus”". TOIN International Symposium on Biomedical Engineering 2010, Toin University of Yokohama. Toin University of Yokohama, 2010.
Nobuaki SHIRAI, Mareki OHTSUJI, Hiroki TOMISAWA, Naomi OHTSUJI, Sachiko HIROSE, Hiromi HAGIWARA. "“Nephrotoxicity of Trichloroethylene Metabolite DCVC in Mice”". Toin International Symposium on Biomedical Engineering 2010 Toin University of Yokohama. Toin University of Yokohama, 2010.
M. Kitabatake、H. Igarashi、T.Toda、M. Ohtsuji、H. Tsurui、S.Hirose、N. Sakaguchi. "“Overexpression of protein phosphatase subunit G5PR that suppresses JNKmediated apoptosis caused the increase of B-1 cells associated with autoimmunity”". 14th INTERNATIONAL CONGRESS OF IMMUNOLOGY Kobe. Kobe, 2010.
M. Obata、R Fujiwara、T. Fujii、Y.Kodera、M. Ohtsuji、T. Shirai、S.Hirose、H. Nishimura. "“Mechanism of Thcell tolerance induced with thetolerogenic protein antigen conjugated with polyethylene glycol” ". 15th INTERNATIONAL CONGRESS OF IMMUNOLOGY Kobe. Kobe, 2010.
S. Hirose、Q. Lin、A. Sato、R.Hou、M. Ohtsuji、H. Tsurui、H.Nishimura、T. Shirai. "“Genetics of autoimmunity”". 14th INTERNATIONAL CONGRESS OF IMMUNOLOGY Kobe（2010年8月22日、27日）. Kobe, 2010.
R. Hou、A. Sato、Q. Lin、M. Ohtsuji、T. Adachi、S. Hirose、T.Tsubata. "“Effect of CD72c allotype on SLE susceptibility”". 14th INTERNATIONAL CONGRESS OF IMMUNOLOGY Kobe（2010年8月22日（～27日））. Kobe, 2010.
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アメリカ臨床病理学会（ASCP）
日本サイトメトリー学会
日本臨床細胞学会
日本臨床免疫学会
日本免疫学会、アメリカ免疫学会、日本病理学会、日本リウマチ学会、日本臨床衛生検査技師会、 神奈川県臨床検査技師会、東京都臨床検査技師会
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平成30年度桐蔭横浜大学エクセレントティーチャー (桐蔭横浜大学, 2019-04-01)
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| 学会等および社会における主な活動 | |
| 学会等および社会における活動 |
日本リウマチ学会 リウマチ相談員 地域住民等への正しいリウマチ性疾患の知識の普及啓発 (2020年12月～現在)
NPO アカデミック・ハラスメントをなくすネットワーク（NAAH） 大学、短期大学、高専、研究所など研究・教育活動の場及びそれに関連する施設に在学、在籍、勤務する人に対して、研究や教育活動の妨害、教育を受ける権利の侵害、差別待遇、いじめ、嫌がらせなどのハラスメントのない環境を確保するための啓蒙活動 (2007.04.01～現在)
NPO法人 青少年科学技術振興会. FIRST Japan 2019 FLL Japan Open, team sparrows, Adviser of Medicine (2018年8月～2019年3月)
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| 芸術、体育実技、課外活動における業績 | |